It has become a wellness focus, but how does marijuana and alcohol impact gut health?

Its awareness has significantly increased in the last decad, becoming a popular topic in both scientific research and public consciousness. While the concept of the gut-brain axis and the importance of the gut microbiome has been studied for decades, it is only recently that the general public has become more aware of the impact of gut health on overall well-being. Here is how alcohol and cannabis affect gut health. More people are questioning how lifestyle choices—especially substance use—impact the digestive system. While alcohol and cannabis are commonly used for social and recreational purposes, they interact with the gut in strikingly different ways. Understanding these differences can help guide healthier decisions, particularly for those prioritizing wellness and long-term health.Alcohol consumption, particularly in excess, has long been associated with poor gut health. Alcohol can damage the lining of the gastrointestinal tract, increase intestinal permeability (commonly known as “leaky gut”), and disturb the balance of the microbiome—the trillions of bacteria help regulate digestion, immune function, and even mood. Heavy drinking promotes the overgrowth of harmful bacteria and reduces beneficial strains like Lactobacillus and Bifidobacterium. This imbalance can trigger inflammation, digestive discomfort, and weaken the gut’s natural defenses. Chronic alcohol use has also been linked to gastrointestinal diseases such as gastritis, ulcers, and inflammatory bowel disease (IBD). Cannabis interacts with the gut through the endocannabinoid system (ECS), a network of receptors help regulate digestion, appetite, and immune response. Unlike alcohol, cannabis does not damage the gut lining or directly alter gut permeability in most users. In fact, some studies suggest cannabinoids like CBD and THC may have anti-inflammatory effects which could benefit conditions such as Crohn’s disease or irritable bowel syndrome (IBS). Cannabis may also indirectly support gut health by reducing stress and anxiety—two factors known to worsen digestive symptoms. However, research is still emerging. Some users report slowed digestion or appetite changes with cannabis use, and smoking cannabis can carry respiratory and cardiovascular risks that don’t directly relate to the gut but may affect overall health. Both alcohol and cannabis can have different effects depending on dose, frequency, and form of consumption. Occasional moderate drinking may have limited gut impact for some individuals, while daily heavy use is clearly harmful. Similarly, cannabis edibles may influence digestion differently than smoking or vaping, and high-THC products can have stronger psychoactive effects. When it comes to gut health, alcohol tends to be a clear disruptor, while cannabis presents a more nuanced profile. While early research shows potential benefits of cannabinoids for gut inflammation and stress-related digestive issues, more clinical studies are needed. For individuals concerned with maintaining a healthy microbiome and digestive system, moderation and informed choices remain key.

The Fresh Toast is a daily lifestyle platform with a side of cannabis. For more information, visit www.thefreshtoast.com.

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